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Think about alternant therapies that aren't average CYP3A inducers in the course of cure with mitapivat. If unable to steer clear of coadministration, monitor Hb and titrate beyond fifty mg BID, if important, but do not exceed mitapivat dose of a hundred mg BID. .pentobarbital boosts effects of ifosfamide by influencing hepatic enzyme CYP2B6 metabo